Download our posters here:

Dr Jure Fabjan: Bridging Pre-Clinical and Clinical Gaps: A Hybrid OMICs and Mechanistic Model for Predicting Drug Response in Liver Cancer.

Dr Mariana Guimaraes: Application of HT-PBPK Modelling for developing an IVIVE of Oral Permeability in OSPsuite.

Dr Susana Proenca: Applying PBK Modeling to Support Animal-free Safety Assessment of Environmental Chemicals: Case Studies for Developmental Neurotoxicity

Dr Wilbert de Witte: Validation and refinement of the large molecule biodistribution model in PK-Sim.

Dr Wilbert de Witte: Continuous infusion simulations in PBPK and QSP models reveal steady-state properties and rate-limiting steps.

Carmine Schiavone: A Modular PBPK–QSP Platform for Translational Modeling of Bispecific TCell Engagers

Pavel Balazki: The R package Ecosystem of the Open Systems Pharmacology – the right tools for User-friendly and Quality-Controlled PBPK/QSP M&S workflows for Regulatory Submissions

Pavel Balazki: Physiologically-Based Quantitative System Toxicology Thyroid Hormones Modeling Platform: Species-dependent Thyroid Hormone Changes by chemical modulators in Rats and Humans

Patrick Kaiser: Asclepius – A Custom GPT for the Open Systems Pharmacology.

Dr Laurence Dodd: Novel Application of OSPSuite v12 for Model-Informed Drug Development of Modified-Release Formulations and Global Sensitivity Analysis (GSA)

The ESQlabs team will be participating in full force at OSPCC 25!

We’ll be leading several workshops, giving talks in sessions, and presenting a variety of posters showcasing the latest updates and advancements in PBPK with OSP Suite.

If you’d like to learn with us, don’t miss the opportunity to join one of our workshops. Out of the six workshops offered this year, four will be led by the ESQlabs team. We’ll cover topics ranging from an introduction to PBPK with PK-Sim to the concept of modularization with the new version 12 of OSP Suite.
⚠️ Please note: The event offers six workshops taking place simultaneously, so you can only choose one — choose wisely!

To participate, register for the event and select one of our workshops. Check them below:

🔷Workshop 1 – Intro PBPK with PK-Sim: This Workshop will provide you with everything you need to get started with PK-Sim for PBPK. Instructor: Dr Stephan Schaller. 

🔷Workshop 4 – PK-Sim for Pediatrics & Spec Pops: This workshop will guide participants through the basis of PBPK modeling using PK-Sim, with a special focus on paediatric, geriatric, and organ-impairment applications. Instructors: Dr Nina Nauwelaerts and Dr Vanessa Baier. 

🔷Workshop 5 – PK-Sim, MoBi, and OSP-R for Pregnancy: This workshop offers a powerful combination of modular, customized PBPK(-QSP) modeling and quality-controlled simulation workflows in R, leveraging the latest advancements in OSP Suite V12. Instructors: Dr Marco Siccardi and Dr Sophie Fischer-Holzhausen.

🔷Workshop 6 – Modular QSP in v12 (PBPK-QSP): This workshop will equip participants with the skills to leverage modular workflows in MoBi to build, extend, and refine PBPK-QSP models, diving into a real-world case study: modeling an ADC modality for tumor treatment. Instructors: Dr Wilbert de Witte and Pavel Balazki. 

Register Now!